Clinical Research

Ethics in Clinical Research

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Clinical Research Methodology 2: Observational Clinical Research.

Case-control and cohort studies are invaluable research tools and provide the strongest feasible research designs for addressing some questions. Case-control studies usually involve retrospective data collection. Cohort studies can involve retrospective, ambidirectional, or prospective data collection. Observational studies are subject to errors attributable to selection bias, confounding, meas...

Clinical research.

bjectives: To review our experience and results in the treatment of a low incidence pathology such as the malignant ear tumors. Methods: The study reviewed 36 patients with malignant tumors of the EAC and middle ear treated between 1977 and 2000 in our hospital, excluding cancer of the pinna, metastatic tumours and sarcomas. It was used the staging system proposed by the M.D. Anderson. Results:...

Clinical research.

Distinguishing between clinical practice and clinical research: A Review of definitions and ethical issues

While Clinical research and clinical practice are closely related, distinguishing and maintaining the boundaries between them has form determining debates in contemporary bioethics. The most important implication of the research-practice distinction is to identify which clinical activities need review and oversight by research ethics committees. Adopting distinct approaches to clinical research...